BioVision Products
Human CellExp™LAG3 /CD223, human recombinant
- SKU:
- 7278-50
Description
Human CellExp™LAG3 /CD223, human recombinant is available at Gentaur for Next week delivery.
A protein involved in lymphocyte activation
Biomolecule/Target: LAG3 /CD223
Alternates names: LAG3, CD223, FDC
Synonyms: LAG3, CD223, FDC
Background Information: Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC. It belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. LAG3/CD223 is one of the inhibitory receptors by negatively regulating cellular proliferation, activation, and homeostasis of T cells. LAG3 can bind to HLA class-II antigens and is involved in lymphocyte activation and autoimmunity. There are now LAG3 targeted therapies both in the clinic and in preclinical development, emphasizing the broad interest in this inhibitory receptor.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4).
NCBI Gene Symbol: LAG3
Gene ID: 3902
NCBI Accession: P18627
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
47 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |