Description
LAG-1 (CCL4L1), Human Recombinant is available at Gentaur for Next week delivery.
LAG-1 is CC chemokine that signals through the CCR5 receptor
Biomolecule/Target: LAG-1 (CCL4L1)
Alternates names: Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21, C-C motif chemokine 4-like, Lymphocyte activation gene 1 protein, LAG-1, Macrophage inflammatory protein 1-beta, MIP-1-beta, Monocyte adherence-induced protein 5-alpha, Small-inducible cytokine A4-like
Synonyms: Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21, C-C motif chemokine 4-like, Lymphocyte activation gene 1 protein, LAG-1, Macrophage inflammatory protein 1-beta, MIP-1-beta, Monocyte adherence-induced protein 5-alpha, Small-inducible cytokine A4-like
Background Information: LAG-1 is CC chemokine receptor (beta chemokine receptors) that signals through the CCR5 receptor. LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
NCBI Gene Symbol:
NCBI Accession: Q8NHW4
Additional Information
Size: |
5 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E.coli |
Purity by SDS-PAGE: |
≥ 98% |
Assay: |
SDS-PAGE |
Endotoxin Level: |
<0.1 EU/μg |
Biological activity: |
Determined by its ability to chemoattract CCR5 transfected cells using a concentration of 0.1-10.0 ng/ml |
Molecular Weight: |
7.7 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |