L-Methionine γ-Lyase, Pseudomonas putida recombinant

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SKU:
7848-500
$719.07
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Description

L-Methionine γ-Lyase, Pseudomonas putida recombinant is available at Gentaur for Next week delivery.

≥90% Pure Active Recombinant L-Methionine γ-Lyase which plays a central role in sulfur amino acid metabolism

Biomolecule/Target: L-Methionine γ-Lyase

Alternates names: L-Methionine-α-deamino-γ-mercaptomethane-Lyase, Methioninase, METase, MGL, mdeA

Synonyms: L-Methionine-α-deamino-γ-mercaptomethane-Lyase, Methioninase, METase, MGL, mdeA

Background Information: Methionine gamma-lyase (EC 4.4.1.11) from Pseudomonas putida is a PLP-dependent enzyme which plays a central role in sulfur amino acid metabolism. METase catalyzes the α, γ-elimination of methionine to α-ketobutyrate, methanethiol, and ammonia. METase also catalyzes the α, γ-elimination of other sulfur containing amino acids, such as homocysteine, cysteine. Because of its ability to deplete methionine, METase has been considered as a viable component of cancer therapeutics against methionine-dependent tumor cells. METase has also been utilized to design drug targets for the infectious diseases caused by parasitic protozoa and anaerobic periodontal bacteria.

Reconstitution Instructions: Briefly spin down and reconstitute in water or phosphate buffer.

NCBI Gene Symbol: mdeA

Gene ID: N/A

NCBI Accession: P13254

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Additional Information

Size:
500 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Pseudomonas putida
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
≥ 0.5 U/mg.
Biological activity:
≥ 0.5 U/mg.
Results:
≥ 0.5 U/mg.
Molecular Weight:
47.1 kDa (1-398 aa, NT Poly-His Tag)
Storage Temperature:
–20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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