KLRK1, human recombinant

KLRK1, human recombinant is available at Gentaur for Next week delivery.

Plays a role as a receptor for the recognition of MHC class I HLA-E molecules

Biomolecule/Target: KLRK1

Alternates names: NKG2-D type II integral membrane protein, CD314, D12S2489E, KLR, NKG2-D, NKG2D

Synonyms: NKG2-D type II integral membrane protein, CD314, D12S2489E, KLR, NKG2-D, NKG2D

Background Information: KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and the genes possess elements of heat shock promoters. MICA and MICB, therefore, are expressed during cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination may play a critical role in the immune response to a variety of pathologies. Recombinant human KLRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Reconstitution Instructions: N/A

NCBI Gene Symbol: KLRK1

Gene ID: 22914

NCBI Accession: P26718