Description
KLRK1, human recombinant is available at Gentaur for Next week delivery.
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules
Biomolecule/Target: KLRK1
Alternates names: NKG2-D type II integral membrane protein, CD314, D12S2489E, KLR, NKG2-D, NKG2D
Synonyms: NKG2-D type II integral membrane protein, CD314, D12S2489E, KLR, NKG2-D, NKG2D
Background Information: KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and the genes possess elements of heat shock promoters. MICA and MICB, therefore, are expressed during cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination may play a critical role in the immune response to a variety of pathologies. Recombinant human KLRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Reconstitution Instructions: N/A
NCBI Gene Symbol: KLRK1
Gene ID: 22914
NCBI Accession: P26718
Additional Information
Size: |
100 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
19.2 kDa (168 aa, 73-216 aa + His Tag), confirmed by MALDI-TOF. |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
0.5 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |