Description
K63-linked Di-Ubiquitin is available at Gentaur for Next week delivery.
Substrate for defined length polyubiquitination
Biomolecule/Target:
Alternates names:
Synonyms: K63-linked Di-Ubiquitin
Background Information: Poly-ubiquitination of target proteins through K63 has recently become the focus of intense study. The topology of this linkage type is quite different from polyubiquitin linked through lysine 48. Modification of proteins by K63-linked polyubiquitination has been implicated in, among other cellular processes, the regulation of the DNA damage response, endosomal sorting, autophagy of misfolded/aggregated proteins, and neurodegeneration. These di-ubiquitin chains are generated from the enzymatic linkage of wild-type ubiquitin through lysine 63. The most distal ubiquitin contains an arginine substitution for a lysine at position 63, limiting chain length.
Reconstitution Instructions: N/A
NCBI Gene Symbol: N/A
Gene ID: N/A
NCBI Accession: N/A
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Rabbit |
Recombinant: |
N/A |
Source: |
N/A |
Purity by SDS-PAGE: |
≥95% |
Assay: |
Western Blot |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
17.139 kDa (Band migrates faster on gels) |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
2.5 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |