K11-linked Di-Ubiquitin

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SKU:
6421-50
€185
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Description

K11-linked Di-Ubiquitin is available at Gentaur for Next week delivery.

Substrate for defined length polyubiquitination

Biomolecule/Target:

Alternates names:

Synonyms: K11-linked Di-Ubiquitin

Background Information: Increasingly, researchers are focusing on the role poly-ubiquitin chains linked through K11. This post-translational modification has been linked to the ERAD cycle as a signal, similar to K48 linkage, for proteasomal degradation. More recently, K11 linkage appears to play an important role in cell cycle signaling, as it is associated with the anaphase promoting complex (APC) of ubiquitination machinery. These di-ubiquitin chains are generated from the enzymatic linkage (UBE2S) of wild-type ubiquitin through lysine 11 and purified to >95% homogeneity by ion exchange chromatography.

Reconstitution Instructions: N/A

NCBI Gene Symbol: N/A

Gene ID: N/A

NCBI Accession: N/A

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Rabbit
Recombinant:
N/A
Source:
N/A
Purity by SDS-PAGE:
≥95%
Assay:
Western Blot
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
17.111 kDa (Band migrates faster on gels)
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
2.5 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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