Irisin, Active, human recombinant

Irisin, Active, human recombinant is available at Gentaur for Next week delivery.

Activates beige fat cells

Biomolecule/Target: Irisin

Alternates names: Fibronectin Type III Domain-containing Protein 5, FNDC5 (cleaved); Fibronectin Type III Repeat-containing Protein 2, FRCP2 (cleaved).

Synonyms: Fibronectin Type III Domain-containing Protein 5, FNDC5 (cleaved); Fibronectin Type III Repeat-containing Protein 2, FRCP2 (cleaved).

Background Information: Irisin is a recently discovered exercise-induced myokine, which is secreted by skeletal muscles and produced by cleavage of the FNDC5. Studies show that Irisin stimulates mitochondria uncoupling protein-1 (UCP-1; a regulator of thermogenic capability of brown fat) expression, so Irisin can upregulate white to brown fat conversion and improve systemic metabolism by increasing energy expenditure. Hence, Irisin is a potential new drug target in the study of metabolic disorders, such as obesity and type 2 diabetes mellitus (T2DM). Moreover, FNDC5-like receptors are conserved in vertebrates and critical for neuronal development.

Reconstitution Instructions: Reconstitute to 0.1 mg/ml with sterile water

NCBI Gene Symbol: FNDC5

Gene ID: 252995

NCBI Accession: Q8NAU1