IL-4, rat recombinant

(No reviews yet) Write a Review
SKU:
4139-50
€185
Frequently bought together:

Description

IL-4, rat recombinant is available at Gentaur for Next week delivery.

A key regulator in humoral and adaptive immunity

Biomolecule/Target: IL-4

Alternates names: BCGF,BCDF, B cell stimulating factor, BSF-1,Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra,

Synonyms: BCGF,BCDF, B cell stimulating factor, BSF-1,Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra,

Background Information: IL4 is a pleiotropic cytokine and a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. The solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: IL4

Gene ID: 287287

NCBI Accession: P20096

View AllClose

Additional Information

Size:
50 μg
Adwords:
Yes- SG
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Rat
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of con A-activated rat spleen cells is < 1.5 ng/ml, corresponding to a specific activity of > 6.6 x 10⁵ units/mg.
Results:
< 1.5 ng/ml
Molecular Weight:
14.1 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose