Description
IL-4, rat recombinant is available at Gentaur for Next week delivery.
A key regulator in humoral and adaptive immunity
Biomolecule/Target: IL-4
Alternates names: BCGF,BCDF, B cell stimulating factor, BSF-1,Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra,
Synonyms: BCGF,BCDF, B cell stimulating factor, BSF-1,Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra,
Background Information: IL4 is a pleiotropic cytokine and a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. The solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
NCBI Gene Symbol: IL4
Gene ID: 287287
NCBI Accession: P20096
Additional Information
Size: |
50 μg |
Adwords: |
Yes- SG |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Rat |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of con A-activated rat spleen cells is < 1.5 ng/ml, corresponding to a specific activity of > 6.6 x 10⁵ units/mg. |
Results: |
< 1.5 ng/ml |
Molecular Weight: |
14.1 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |