IL-13, rat recombinant

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SKU:
4166-1000
€185
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Description

IL-13, rat recombinant is available at Gentaur for Next week delivery.

A mediator of allergic inflammation and disease

Biomolecule/Target: IL-13

Alternates names: NC30, ALRH, BHR1, P600, IL-13, MGC116786, MGC116788, MGC116789.

Synonyms: NC30, ALRH, BHR1, P600, IL-13, MGC116786, MGC116788, MGC116789.

Background Information: IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having similar structural features and functional characteristics as IL-4, but only shares ~30% homolog with the IL-4 sequence. IL-13 inhibits IL-1β, IL-6, IL-8, and TNF-α resulting in anti-inflammatory effects on monocytes and macrophages. IL-13 also induces B cells to proliferate and modulating TH2 cell development. Recombinant rat IL-13 is an 11.9 kDa protein containing 109 amino acid residues.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: IL13

Gene ID: 116553

NCBI Accession: P42203

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Additional Information

Size:
1 mg
Adwords:
Yes-SG
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Rat
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
≥95%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells was typically 2-6 ng/ml.
Results:
2-6 ng/ml
Molecular Weight:
12.7 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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