ICOSLG /B7-H2 /CD275, mouse recombinant

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SKU:
P1106-50
$183
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Description

ICOSLG /B7-H2 /CD275, mouse recombinant is available at Gentaur for Next week delivery.

Ligand for the T-cell-specific cell surface receptor ICOS

Biomolecule/Target: Icoslg

Alternates names: B7-H2, ICOS Ligand, B7-like Protein Gl50, B7RP-1

Synonyms: B7-H2, ICOS Ligand, B7-like Protein Gl50, B7RP-1

Background Information: Mouse CD275 (B7-H2) is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is expressed on resting B cells and at low levels on monocytes. The CD275/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

Reconstitution Instructions: Reconstitute at 100 μg/ml in sterile PBS

NCBI Gene Symbol: Icoslg

Gene ID: 50723

NCBI Accession: Q9JHJ8

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Additional Information

Size:
50 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
CHO cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 0.06 EU/μg
Activity (Specifications/test method):
Measured by its binding ability in a functional ELISA.
Biological activity:
Immobilized human ICOS at 1μg/ml (100μl/well) can bind biotinylated B7-H2 (mouse), Fc (mouse) (rec.) (non-lytic) with a linear range of 0.1-1.0μg/ml.
Results:
N/A
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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