BioVision Proteins
ICOSLG /B7-H2 /CD275, mouse recombinant
- SKU:
- P1106-50
Description
ICOSLG /B7-H2 /CD275, mouse recombinant is available at Gentaur for Next week delivery.
Ligand for the T-cell-specific cell surface receptor ICOS
Biomolecule/Target: Icoslg
Alternates names: B7-H2, ICOS Ligand, B7-like Protein Gl50, B7RP-1
Synonyms: B7-H2, ICOS Ligand, B7-like Protein Gl50, B7RP-1
Background Information: Mouse CD275 (B7-H2) is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is expressed on resting B cells and at low levels on monocytes. The CD275/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
Reconstitution Instructions: Reconstitute at 100 μg/ml in sterile PBS
NCBI Gene Symbol: Icoslg
Gene ID: 50723
NCBI Accession: Q9JHJ8
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Mouse |
Recombinant: |
Yes |
Source: |
CHO cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 0.06 EU/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Immobilized human ICOS at 1μg/ml (100μl/well) can bind biotinylated B7-H2 (mouse), Fc (mouse) (rec.) (non-lytic) with a linear range of 0.1-1.0μg/ml. |
Results: |
N/A |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |