Human Tau-383

Human Tau-383 is available at Gentaur for Next week delivery.

A tau isoform

Biomolecule/Target:

Alternates names: Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; mAP; MAPTL; MTBT1; Tau 0N4R; tau isoform 3; ht24; 4RS tau; Isoform Tau-D

Synonyms: Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; mAP; MAPTL; MTBT1; Tau 0N4R; tau isoform 3; ht24; 4RS tau; Isoform Tau-D

Background Information: Tau is a neuronal microtubule-associated protein. It stabilizes microtubules in axons. Tau protein become hyperphosphorylated and forms insoluble aggregates called neurofibrillary tangles in Alzheimer's disease. The accumulation of abnormal tau aggregates causes cytoxicity, which is described as a gain-of-toxic function model. Tau gene undergoes alternative splicing, giving rise to six different isoforms. Tau-383 isoform contains exon 10 and lacks exons 2 and 3.

Reconstitution Instructions:

NCBI Gene Symbol:

Gene ID:

NCBI Accession: P10636; NP_058518