Human Recombinant Glyoxalase I

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SKU:
6389-100
€185
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Description

Human Recombinant Glyoxalase I is available at Gentaur for Next week delivery.

Involved in the pathophysiology of mood disorders

Biomolecule/Target:

Alternates names: Lactoylglutathione lyase, Glx 1, GLO-1 Methylglyoxalase, Aldoketomutase

Synonyms: Human Recombinant Glyoxalase I

Background Information: GLO1 is involved in the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutathione. GLO1 is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. GLO1 enzyme is abundantly expressed and present in numerous tumor cell lines, in which its concentration is often upregulated ubiquitously. GLO1 is a major susceptible gene for autism in an ethnic Chinese population from Taiwan. GLO1 might be involved in the pathophysiology of mood disorders. GLO1 plays a role in the pathophysiology of mood disorders. Overexpression of GLO1 is associated with kidney tumor.

Reconstitution Instructions: N/A

NCBI Gene Symbol: GLO1

Gene ID: 2739

NCBI Accession: Q04760

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity: >0.4 units/mg.
Results:
>0.4 units/mg
Molecular Weight:
20.7 kDa (184 aa, 1-184 aa)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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