Human CellExp™ VEGF R3, Fc Tag, human recombinant

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SKU:
P1148-50
£135.37
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Description

Human CellExp™ VEGF R3, Fc Tag, human recombinant is available at Gentaur for Next week delivery.

Cell-surface receptor for VEGFC and VEGFD

Biomolecule/Target: FLT4

Alternates names: Flt-4, FLT4, LMPH1A, PCLFLT41, VEGFR3, VEGFR-3, FLT-4, FLT-41, FLT41, PCL

Synonyms: Flt-4, FLT4, LMPH1A, PCLFLT41, VEGFR3, VEGFR-3, FLT-4, FLT-41, FLT41, PCL

Background Information: Vascular endothelial growth factor receptor 3 (VEGF R3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). VEGF R3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: FLT4

Gene ID: 2324

NCBI Accession: P35916

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK 293 cells
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per/μg
Activity (Specifications/test method):
Measured by its binding ability in a functional ELISA.
Biological activity:
Immobilized Human VEGF-C, His Tag at 5μg/mL (100 μL/well) can bind Human VEGF R3, Fc Tag with a linear range of 0.6-10 ng/mL. Immobilized Human VEGF R3, Fc Tag at 5μg/mL (100 μL/well) can bind Human VEGF-D, His Tag, Strep Tag with a linear range of 0
Results:
N/A
Molecular Weight:
111.2 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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