BioVision Proteins
Human CellExp™ VEGF R3 / FLT4, Fc Tag, Mouse Recombinant
- SKU:
- P1405-50
Description
Human CellExp™ VEGF R3 / FLT4, Fc Tag, Mouse Recombinant is available at Gentaur for Next week delivery.
Cell-surface receptor for VEGFC and VEGFD
Biomolecule/Target:
Alternates names: Flt-4, FLT4, LMPH1A, PCLFLT41, VEGFR3, VEGFR-3, FLT-4, FLT-41, FLT41, PCL
Synonyms: Flt-4, FLT4, LMPH1A, PCLFLT41, VEGFR3, VEGFR-3, FLT-4, FLT-41, FLT41, PCL
Background Information: Vascular endothelial growth factor receptor 3 (VEGF R3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). VEGF R3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: Flt4
Gene ID: 14257
NCBI Accession: P35917-1
Additional Information
Size: |
50 µg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Murine |
Recombinant: |
True |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>95% |
Assay: |
SDS-PAGE. |
Endotoxin Level: |
Less than 0.1 EU per μg by the LAL method. |
Activity (Specifications/test method): |
Immobilized Human VEGF-C, His Tag at 5 μg/mL (100 μL/well) can bind Mouse VEGF R3, Mouse Fc Tag, low endotoxin with a linear range of 1-10 ng/mL |
Molecular Weight: |
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 111.5 kDa. The protein migrates as 116-125 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |