Human CellExp™ TIM3/HAVR2 Protein, Human Recombinant

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SKU:
P1002-20
€185
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Description

Human CellExp™ TIM3/HAVR2 Protein, Human Recombinant is available at Gentaur for Next week delivery.

TIM3 inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

Biomolecule/Target: TIM3/HAVR2

Alternates names: Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3

Synonyms: Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3

Background Information: Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH7.4) to a stock solution of 400 µg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.

NCBI Gene Symbol: HAVCR2

Gene ID: 84868

NCBI Accession: Q8TDQ0

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Additional Information

Size:
20 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK 293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<0.01 EU/μg
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 20.7 kDa. The predicted N-terminus is Ser 22. DTT-reduced Protein migrates as 28-48 kDa due to glycosylation.
Storage Temperature:
4°C in lyophilized state
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Dry powder
Handling:
Centrifuge the vial prior to opening.
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