Human CellExp™ PSMA / FOLH1, C-His Tag, human recombinant

Human CellExp™ PSMA / FOLH1, C-His Tag, human recombinant is available at Gentaur for Next week delivery.

Extracellular Domain of PSMA fused to 6x His tag at the C-terminus.

Biomolecule/Target: PSMA

Alternates names: Prostatespecific membrane antigen; Glutamate carboxypeptidase 2; PSMA; PSM; mGCP; GCPII; FGCP; NAALADase I; cell growth-inhibiting gene 27 protein; Folate hydrolase 1; Folylpoly gamma glutamate carboxypeptidase; glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Pteroylpoly-gamma-glutamate carboxypeptidase

Synonyms: Prostatespecific membrane antigen; Glutamate carboxypeptidase 2; PSMA; PSM; mGCP; GCPII; FGCP; NAALADase I; cell growth-inhibiting gene 27 protein; Folate hydrolase 1; Folylpoly gamma glutamate carboxypeptidase; glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Pteroylpoly-gamma-glutamate carboxypeptidase

Background Information: Human Prostate Specific Membrane Antigen (PSMA), a tumor marker in prostate cancer encoded by FOLH1 gene, is a surface glycoprotein with high expression in prostate epithelium. PSMA expression level increases in primary and metastatic prostate cancer and the neovasculature of nonprostatic epithelial malignancies. Overexpression of PSMA is correlated with high tumor grade, non-diploid tumors, and advanced tumor stage. PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It is also recognized as a viable target for cancer therapy.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in PBS (pH 7.4). Do not vortex.

NCBI Gene Symbol: PSMA

Gene ID: 2346

NCBI Accession: Q04609