BioVision Proteins
Human CellExp™ Properdin, Human Recombinant
- SKU:
- P1470-50
Description
Human CellExp™ Properdin, Human Recombinant is available at Gentaur for Next week delivery.
A positive regulator of the alternate pathway of complement
Biomolecule/Target:
Alternates names: Properdin, Complement factor P, CFP, PFC
Synonyms: Properdin, Complement factor P, CFP, PFC
Background Information: Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: CFP
Gene ID: 5199
NCBI Accession: P27918
Additional Information
Size: |
50 µg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
True |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>90% |
Assay: |
SDS-PAGE |
Endotoxin Level: |
Less than 1.0 EU per μg by the LAL method. |
Molecular Weight: |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |