Human CellExp™ PLGF / PGF, Rhesus macaque Recombinant

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SKU:
P1393-50
£135.37
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Description

Human CellExp™ PLGF / PGF, Rhesus macaque Recombinant is available at Gentaur for Next week delivery.

A key molecule in angiogenesis and vasculogenesis

Biomolecule/Target:

Alternates names: PGF, PLGF, PlGF2, PlGF, PGFL, SHGC-10760

Synonyms: PGF, PLGF, PlGF2, PlGF, PGFL, SHGC-10760

Background Information: Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile deionized water. Do not vortex. It is recommended to store at -20°C.

NCBI Gene Symbol: PGF

Gene ID: 701219

NCBI Accession: F7HB10

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Additional Information

Size:
50 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Rhesus macaque
Recombinant:
FAUX
Source:
HEK 293 cells
Purity by SDS-PAGE:
>90% as determined by SDS-PAGE
Endotoxin Level:
Less than 1.0 EU per μg by the LAL method
Activity (Specifications/test method):
Immobilized Rhesus macaque VEGF R1, Mouse IgG2a Fc Tag, low endotoxin at 5 μg/mL (100 μL/well) can bind Rhesus macaque PLGF with a linear range of 2-40 ng/mL
Molecular Weight:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.3 kDa. The protein migrates as 28-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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