Description
Human CellExp™ Mesothelin / MSLN, Human Recombinant is available at Gentaur for Next week delivery.
Membrane-anchored forms may play a role in cellular adhesion.
Biomolecule/Target: Mesothelin
Alternates names: MSLN, Mesothelin, MPF, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor
Synonyms: MSLN, Mesothelin, MPF, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor
Background Information: Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.
NCBI Gene Symbol: MSLN
Gene ID: 10232
NCBI Accession: Q13421
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Immobilized Human Mesothelin, His Tag at 0.5 μg/mL (100 μL/well) can bind Anti-Human MSLN Mab with a linear range of 0.1-2 ng/mL |
Results: |
N/A |
Molecular Weight: |
33.0 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |