BioVision Products
Human CellExp™ LEFTY-I, Human Recombinant
- SKU:
- 4873-50
Description
Human CellExp™ LEFTY-I, Human Recombinant is available at Gentaur for Next week delivery.
Plays a role in left-right asymmetry determination of organ systems during development
Biomolecule/Target:
Alternates names: Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B
Synonyms: Human Recombinant LEFTY-I
Background Information: BioVision’s LEFTY-1 is expressed in human 293 cells as a monomeric glycoprotein with an apparent molecular mass of 38 kDa. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media. Lefty proteins function as an antagonist of the Nodal Signaling pathway. Proper functioning of Lefty is crucial to the proper development of the heart, lungs, spleen, and liver.
Reconstitution Instructions: Reconstitute in sterile water.
NCBI Gene Symbol: LEFTY1
Gene ID: 10637
NCBI Accession: O75610
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Human 293 cells |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The specific activity was determined by dose dependent ability to inhibit BMP-4 (6.5 ng/mL) induction of alkaline phosphatase production in the MC-3T3-E1 cell line (Mouse Chondrogenic cell line). |
Results: |
Typically 10 to 40 ng/mL ED50. |
Molecular Weight: |
38 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |