Human CellExp™ LAG3 / CD223, Fc Tag, human recombinant

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SKU:
P1149-50
€185
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Description

Human CellExp™ LAG3 / CD223, Fc Tag, human recombinant is available at Gentaur for Next week delivery.

A protein involved in lymphocyte activation

Biomolecule/Target: LAG3

Alternates names: LAG3, CD223, FDC

Synonyms: LAG3, CD223, FDC

Background Information: Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: LAG3

Gene ID: 3902

NCBI Accession: P18627

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK 293 cells
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per/μg
Activity (Specifications/test method):
Measured by its binding ability in a functional ELISA.
Biological activity:
Immobilized Human LAG-3, Fc Tag at 2μg/mL (100 μL/well) can bind Anti-LAG3 MAb, Human IgG1 with a linear range of 0.1-2 ng/mL.
Results:
N/A
Molecular Weight:
72.3 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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