Human CellExp™ Integrin alpha 6 beta 1 Heterodimer, Human Recombinant

Human CellExp™ Integrin alpha 6 beta 1 Heterodimer, Human Recombinant is available at Gentaur for Next week delivery.

Hetrodimer integrin (alpha 6 beta 1) negatively regulate erbB2/HER2 signaling

Biomolecule/Target: ITGA6, ITGB1

Alternates names: Integrin alpha 6 beta 1, ITGA6B1, ITGA6&ITGB1, CD49f, VLA-6

Synonyms: Integrin alpha 6 beta 1, ITGA6B1, ITGA6&ITGB1, CD49f, VLA-6

Background Information: Integrin alpha 6 beta 1, also called platelet glycoprotein GPIc-IIa, is a receptor for laminin on platelets. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. ITGA6 has been shown to interact with TSPAN4 and GIPC1.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: ITGA6, ITGB1

Gene ID: 3655, 3688

NCBI Accession: P23229, P05556