BioVision Products
Human CellExp™ TGF-beta 1, Human Recombinant
- SKU:
- 6479-50
Description
Human CellExp™ TGF-beta 1, Human Recombinant is available at Gentaur for Next week delivery.
A protein that controls proliferation, cellular differentiation, & other functions in most cells
Biomolecule/Target:
Alternates names: Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1.
Synonyms: Human Cellexp Human Recombinant TGF-beta 1
Background Information: Transforming growth factor betas (TGFβ) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 1 is involved in hematopoiesis and endothelial differentiation.
Reconstitution Instructions: Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.
NCBI Gene Symbol: TGFB1
Gene ID: 7040
NCBI Accession: P01137
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
China |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Human 293 cell expressed |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 μg of protein |
Activity (Specifications/test method): |
N/A |
Biological activity: |
ED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2). |
Results: |
0.1 to 0.5 ng/ml |
Molecular Weight: |
25 kDa, homodimer, nonglycosylated |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |