Human CellExp™ IL7Ra/CD127, human recombinant

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SKU:
7492-50
$183
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Description

Human CellExp™ IL7Ra/CD127, human recombinant is available at Gentaur for Next week delivery.

A receptor for IL-7 and TSLP

Biomolecule/Target: IL7Ra/CD127

Alternates names: IL7Ra, CD127

Synonyms: IL7Ra, CD127

Background Information: Interleukin-7 receptor subunit alpha (IL7Ra) also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: IL17Ra

Gene ID: 23765

NCBI Accession: Q96F46

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<1 EU/μg by LAL method
Activity (Specifications/test method):
N/A
Biological activity:
Measured by its binding ability in a functional ELISA. Immobilized rhIL7Ra Fc Chimera at 0.25 μg/ml (100 μl/well) on a Rabbit anti‑human IgG Fc antibody, the concentration of rhIL-7 that produces 50% of the optimal binding response is found to be app
Results:
Measured by its binding ability in a functional ELISA. Immobilized rhIL7Ra Fc Chimera at 0.25 μg/ml (100 μl/well) on a Rabbit anti‑human IgG Fc antibody, the concentration of rhIL-7 that produces 50% of the optimal binding response is found to be app
Molecular Weight:
This protein is fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 51 kDa. The predicted N-terminus is Glu 21. DTT-reduced Protein migrates as 66-90 kDa due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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