BioVision Products
Human CellExp™ IL7Ra/CD127, human recombinant
- SKU:
- 7492-50
Description
Human CellExp™ IL7Ra/CD127, human recombinant is available at Gentaur for Next week delivery.
A receptor for IL-7 and TSLP
Biomolecule/Target: IL7Ra/CD127
Alternates names: IL7Ra, CD127
Synonyms: IL7Ra, CD127
Background Information: Interleukin-7 receptor subunit alpha (IL7Ra) also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: IL17Ra
Gene ID: 23765
NCBI Accession: Q96F46
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its binding ability in a functional ELISA. Immobilized rhIL7Ra Fc Chimera at 0.25 μg/ml (100 μl/well) on a Rabbit anti‑human IgG Fc antibody, the concentration of rhIL-7 that produces 50% of the optimal binding response is found to be app |
Results: |
Measured by its binding ability in a functional ELISA. Immobilized rhIL7Ra Fc Chimera at 0.25 μg/ml (100 μl/well) on a Rabbit anti‑human IgG Fc antibody, the concentration of rhIL-7 that produces 50% of the optimal binding response is found to be app |
Molecular Weight: |
This protein is fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 51 kDa. The predicted N-terminus is Glu 21. DTT-reduced Protein migrates as 66-90 kDa due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |