Description
Human CellExp™IL-2, Human Recombinant is available at Gentaur for Next week delivery.
A regulator of lymphocyte activities
Biomolecule/Target:
Alternates names: T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2.
Synonyms: T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2.
Background Information: Interleukin-2 (IL-2) is a potent immuno-modulator, which mediates a wide range of immune and inflammatory responses and is important for the proliferation of T and B lymphocytes. IL-2 is one of the key cytokines for the immune system, tolerance and immunity. It has been approved for the treatment of metastatic renal cell carcinoma and metastatic melanoma in cancer immunotherapy with long term disease control. In addition to being used as monotherapy, IL-2 can also be combined with other anticancer immunotherapies, such as adoptive cell transfer, vaccination, and blockade of immune checkpoint inhibitory molecules, such as cytotoxic T lymphocyte-associated antigen 4 and programmed death 1 monoclonal-antibodies as a promising treatment for metastatic cancer.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
NCBI Gene Symbol: IL2
Gene ID: 3558
NCBI Accession: P60568
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
FAUX |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
> 95% by SDS - PAGE |
Activity (Specifications/test method): |
ED50 is typically 0.2 to 2 ng/mL. The specific activity was determined by the dose dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell line) using BioVision’s Quick Cell Proliferation colorimetric Assay Kit Plus ( |
Molecular Weight: |
16 kDa with a 6×His tag at the C-terminus |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |