Human CellExp™ IL-12 R beta 1 / CD212, Fc Tag, Human Recombinant

Human CellExp™ IL-12 R beta 1 / CD212, Fc Tag, Human Recombinant is available at Gentaur for Next week delivery.

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction.

Biomolecule/Target:

Alternates names: IL-12 R beta 1, IL12RB1, CD212, IL12R, IL12RB, IL-12RB1

Synonyms: IL-12 R beta 1, IL12RB1, CD212, IL12R, IL12RB, IL-12RB1

Background Information: The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: IL12RB1

Gene ID: 3594

NCBI Accession: P42701