Human CellExp™ Frizzled-4 / FZD4 Protein, Human recombinant

Human CellExp™ Frizzled-4 / FZD4 Protein, Human recombinant is available at Gentaur for Next week delivery.

Biomolecule/Target: FZD4

Alternates names: FZD4, Frizzled-4, CD344, Fz-4, hFz4, FzE5

Synonyms: FZD4, Frizzled-4, CD344, Fz-4, hFz4, FzE4

Background Information: Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex.

NCBI Gene Symbol: FZD4

Gene ID: 8322

NCBI Accession: Q9ULV1