BioVision Products
Human CellExp™ CD87 / uPAR / PLAUR, human recombinant
- SKU:
- 7372-20
Description
Human CellExp™ CD87 / uPAR / PLAUR, human recombinant is available at Gentaur for Next week delivery.
Acts as a receptor for urokinase plasminogen activator
Biomolecule/Target: CD87/uPAR/PLAUR
Alternates names: uPAR, PLAUR, CD87, MO3
Synonyms: uPAR, PLAUR, CD87, MO3
Background Information: Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR act as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: PLAUR
Gene ID: 5329
NCBI Accession: Q03405
Additional Information
Size: |
20 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥92% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 μg/ml (100 μl/well) can bind biotinylated human UPA with a linear range of 25 - 500 ng/ml. |
Results: |
Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 μg/ml (100 μl/well) can bind biotinylated human UPA with a linear range of 25 - 500 ng/ml. |
Molecular Weight: |
This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 32.1 kDa. The predicted N-terminus is Leu 23. DTT-reduced Protein migrates as 44-48 kDa due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |