Human CellExp™ CD58 / LFA-3, Fc Tag, human recombinant

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SKU:
P1150-50
€185
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Description

Human CellExp™ CD58 / LFA-3, Fc Tag, human recombinant is available at Gentaur for Next week delivery.

Ligand of T-lymphocyte CD2 glycoprotein

Biomolecule/Target: CD58

Alternates names: CD58, LFA3, Ag3

Synonyms: CD58, LFA3, Ag3

Background Information: CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: CD58

Gene ID: 965

NCBI Accession: P19256

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK 293 cells
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per/μg
Activity (Specifications/test method):
Measured by its binding ability in a functional ELISA.
Biological activity:
Immobilized Human CD2, His Tag at 2 μg/mL (100 μL/well) can bind Human CD58, Fc Tag with a linear range of 10-156 ng/mL
Results:
N/A
Molecular Weight:
48.1 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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