BioVision Products
Human CellExp™ CD48 / BCM1 / SLAMF2, human recombinant
- SKU:
- 7380-50
Description
Human CellExp™ CD48 / BCM1 / SLAMF2, human recombinant is available at Gentaur for Next week delivery.
Facilitates interaction between activated lymphocytes
Biomolecule/Target: CD48/BCM1/SLAMF2
Alternates names: CD48, BCM1, SLAMF2, BLAST1, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1
Synonyms: CD48, BCM1, SLAMF2, BLAST1, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1
Background Information: CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: CD48
Gene ID: 962
NCBI Accession: P09326
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its binding ability in a functional ELISA. Immobilized human CD244 protein Fc Chimera at 5 μg/ml (100 μl/well) can bind human CD48 with a linear range of 0.1 - 4 μg/ml. |
Results: |
Measured by its binding ability in a functional ELISA. Immobilized human CD244 protein Fc Chimera at 5 μg/ml (100 μl/well) can bind human CD48 with a linear range of 0.1 - 4 μg/ml. |
Molecular Weight: |
This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 23.2 kDa. The predicted N-terminus is Gln 27. DTT-reduced Protein migrates as 38-45 kDa due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |