Human CellExp™ CD38, Mouse Recombinant

Human CellExp™ CD38, Mouse Recombinant is available at Gentaur for Next week delivery.

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate

Biomolecule/Target: CD38

Alternates names: CD38, T10, cADPr hydrolase 1

Synonyms: CD38, T10, cADPr hydrolase 1

Background Information: CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

NCBI Gene Symbol: CD38

Gene ID: 12494

NCBI Accession: P56528