Human CellExp™ CD319 / SLAMF7 / CRACC, Human Recombinant

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SKU:
7376-50
$719.07
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Description

Human CellExp™ CD319 / SLAMF7 / CRACC, Human Recombinant is available at Gentaur for Next week delivery.

Mediates NK cell activation

Biomolecule/Target: CD319/SLAMF7/CRACC

Alternates names: SLAMF7, CD319, CS1, CRACC, 19A, FOAP-12

Synonyms: SLAMF7, CD319, CS1, CRACC, 19A, FOAP-12

Background Information: SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.

Reconstitution Instructions: Centrifuge the vial prior to opening. Do not vortex. Reconstitute in distilled water to a concentration of at least 100 µg/ml. Store aliquots at -20 °C.

NCBI Gene Symbol: SLAMF7

Gene ID: 57823

NCBI Accession: Q9NQ25

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<1 EU/μg by LAL method
Activity (Specifications/test method):
N/A
Biological activity:
Measured by its ability to bind biotinylated human SLAMF7 in a functional ELISA.
Results:
Measured by its ability to bind biotinylated human SLAMF7 in a functional ELISA.
Molecular Weight:
This protein is fused with 6×His tag at the C-terminus and has a predicted MW of 23.4 kDa. Protein migrates as 32-50 kDa under reducing conditions due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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