BioVision Products
Human CellExp™ CD319 / SLAMF7 / CRACC, Human Recombinant
- SKU:
- 7376-50
Description
Human CellExp™ CD319 / SLAMF7 / CRACC, Human Recombinant is available at Gentaur for Next week delivery.
Mediates NK cell activation
Biomolecule/Target: CD319/SLAMF7/CRACC
Alternates names: SLAMF7, CD319, CS1, CRACC, 19A, FOAP-12
Synonyms: SLAMF7, CD319, CS1, CRACC, 19A, FOAP-12
Background Information: SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.
Reconstitution Instructions: Centrifuge the vial prior to opening. Do not vortex. Reconstitute in distilled water to a concentration of at least 100 µg/ml. Store aliquots at -20 °C.
NCBI Gene Symbol: SLAMF7
Gene ID: 57823
NCBI Accession: Q9NQ25
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its ability to bind biotinylated human SLAMF7 in a functional ELISA. |
Results: |
Measured by its ability to bind biotinylated human SLAMF7 in a functional ELISA. |
Molecular Weight: |
This protein is fused with 6×His tag at the C-terminus and has a predicted MW of 23.4 kDa. Protein migrates as 32-50 kDa under reducing conditions due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |