Human CellExp™ CD30 /TNFRSF8, human recombinant

Human CellExp™ CD30 /TNFRSF8, human recombinant is available at Gentaur for Next week delivery.

May play a role in the regulation of cellular growth and transformation of activated lymphoblasts

Biomolecule/Target: CD30 /TNFRSF8

Alternates names: TNFRSF8, CD30, D1S166E, Ki-1

Synonyms: TNFRSF8, CD30, D1S166E, Ki-1

Background Information: Human CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: TNFRSF8

Gene ID: 943

NCBI Accession: P28908