BioVision Proteins

Human CellExp™ CD3 epsilon & CD3 delta Heterodimer

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SKU:: P1183-10
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$719.07

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Description

Human CellExp™ CD3 epsilon & CD3 delta Heterodimer is available at Gentaur for Next week delivery.

T cell receptor plays an important role in coupling antigen recognition

Biomolecule/Target: CD3E, CD3D

Alternates names: CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon

Synonyms: CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon

Background Information: T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: CD3E, CD3D

Gene ID: 916, 915

NCBI Accession: P07766, P04234

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Additional Information

Size:	10 μg
Country of Manufacturing Origin:	USA
Country of Animal Origin:	USA
Gene Source:	Human
Recombinant:	Yes
Source:	Expi293 cells
Purity by SDS-PAGE:	>95%
Assay:	SDS-PAGE
Purity:	N/A
Assay 2:	N/A
Endotoxin Level:	< 1.0 EU per/μg
Activity (Specifications/test method):	Measured by its binding ability in a functional ELISA.
Biological activity:	Human CD3 epsilon & CD3 delta Heterodimer Protein was immobilized at 0.5 µg/ml (100 µl/well). Dose response curve using Anti-hCD3E/CD3D Ab foralumab gave an EC₅₀ of 21.69 ng/ml by ELISA. Human CD3 epsilon & CD3 delta Heterodimer Protein was Immobiliz
Results:	N/A
Molecular Weight:	16.7 kDa and 13.5 kDa
Storage Temperature:	-80°C
Shelf Life:	12 months
Concentration:	N/A
Appearance:	Lyophilized
Handling:	Centrifuge the vial prior to opening.