BioVision Proteins
Human CellExp™ CD28, Human recombinant
- SKU:
- 9237-100
Description
Human CellExp™ CD28, Human recombinant is available at Gentaur for Next week delivery.
T-cell-specific surface glycoprotein CD29
Biomolecule/Target: CD28
Alternates names: CD28, Tp44
Synonyms: CD28, Tp44
Background Information: T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Reconstitution Instructions: Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml
NCBI Gene Symbol: CD28
Gene ID: 940
NCBI Accession: AAH93698
Additional Information
Size: |
100 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
≥92% |
Assay: |
SDS-PAGE |
Purity: |
≥92% |
Assay 2: |
N/A |
Endotoxin Level: |
< 1 EU/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Immobilized human CD28 at 2 μg/mL (100 μL/well) can bind human Biotin-B7-1 (CD80) Fc with a linear range of 0.01-0.5 μg/mL when detected by Streptavidin-HRP second antibody. |
Results: |
N/A |
Molecular Weight: |
This protein is fused with a Fc tag at C-terminus and has a calculated MW of 41.8 kDa. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |