Human CellExp™ CD27 / TNFRSF7, Fc Tag, Mouse Recombinant

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SKU:
P1406-50
€185
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Description

Human CellExp™ CD27 / TNFRSF7, Fc Tag, Mouse Recombinant is available at Gentaur for Next week delivery.

Member of Tumor necrosis factor receptor superfamily, play a role in survival of activated T-cells and in apoptosis through association with SIVA1.

Biomolecule/Target:

Alternates names: CD27, TNFRSF7, S152, T14, Tp55

Synonyms: CD27, TNFRSF7, S152, T14, Tp55

Background Information: CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: Cd27

Gene ID: 21940

NCBI Accession: P41272-1

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Additional Information

Size:
50 µg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Murine
Recombinant:
True
Source:
HEK 293 cells
Purity by SDS-PAGE:
>95%
Assay:
SDS-PAGE
Endotoxin Level:
Less than 0.1 EU per μg by the LAL method
Activity (Specifications/test method):
Immobilized Mouse CD27, Mouse IgG2a Fc Tag at 2 μg/mL (100 μL/well) can bind Biotinylated Mouse CD70, His Tag, Avi Tag with a linear range of 1-16 ng/m. Immobilized Mouse CD27, Mouse IgG2a Fc Tag at 2 μg/mL (100 μL/well) can bind Biotinylated Human C
Molecular Weight:
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 45.1 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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