Human CellExp™ CD147, human recombinant

Human CellExp™ CD147, human recombinant is available at Gentaur for Next week delivery.

Plays a role in the intercellular recognition involved in various immunologic phenomena

Biomolecule/Target: CD147

Alternates names: Basigin, BSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF.

Synonyms: Basigin, BSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF.

Background Information: CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: BSG

Gene ID: 682

NCBI Accession: P35613