Human CellExp™ BAFFR / TNFRSF13C, Fc Tag Human Recombinant

Human CellExp™ BAFFR / TNFRSF13C, Fc Tag Human Recombinant is available at Gentaur for Next week delivery.

Promotes the survival of mature B-cells and the B-cell response

Biomolecule/Target: TNFRSF13C

Alternates names: BAFFR, TNFRSF13C, BAFF-R, BROMIX, CD268, CVID4, prolixin

Synonyms: BAFFR, TNFRSF13C, BAFF-R, BROMIX, CD268, CVID4, prolixin

Background Information: BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration up to 0.2 mg/ml.

NCBI Gene Symbol: TNFRSF13C

Gene ID: 115650

NCBI Accession: Q96RJ3