Human CellExp™ Acetylcholinesterase / AChE, Human Recombinant

Human CellExp™ Acetylcholinesterase / AChE, Human Recombinant is available at Gentaur for Next week delivery.

Biomolecule/Target:

Alternates names: Acetylcholinesterase (EC:3.1.1.7), AChE

Synonyms: Acetylcholinesterase (EC:3.1.1.7), AChE

Background Information: Acetylcholinesterase (AChE) is the major enzyme that hydrolyzes acetylcholine, a key neurotransmitter for synaptic transmission, into acetic acid and choline in both central and peripheral nervous systems. Mild inhibition of AChE has been shown to have therapeutic relevance in Alzheimer's disease (AD), myasthenia gravis, and glaucoma among others. In contrast, strong inhibition of AChE can lead to cholinergic poisoning. An irregular expression of AChE has also been found in different types of tumors, suggesting the involvement of AChE in the regulation of tumor development. Therefore AChE inhibitors could potentially be used in cancer treatment in future.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.

NCBI Gene Symbol: ACHE

Gene ID: 43

NCBI Accession: P22303