Heregulin-β2 (HRG2β), Human Recombinant

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SKU:
4730-50
$183
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Description

Heregulin-β2 (HRG2β), Human Recombinant is available at Gentaur for Next week delivery.

A signaling protein for ErbB2/ErbB4 receptor

Biomolecule/Target:

Alternates names: Neuregulin-1, NRG1, GGF, HGL, HRGA, NDF, SMDF, HRG, ARIA, GGF2, HRG1

Synonyms: Heregulin-β2 (HRG2β), Human Recombinant

Background Information: Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms release soluble growth factors. HRG-β2 is a signaling protein for ErbB2/ErbB4 receptor on the cardiac muscle cells. The polypeptide is comprised of an immunoglobulin and epidermal growth factor-like (EGF-like) domains.

Reconstitution Instructions: N/A

NCBI Gene Symbol: NRG1

Gene ID: 3084

NCBI Accession: Q02297

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
≥95%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng per µg of Heregulin-β1
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
7.4 kDa (65 aa, 177-237)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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