Guanylate kinase, human recombinant

Guanylate kinase, human recombinant is available at Gentaur for Next week delivery.

Essential for recycling GMP and indirectly, cGMP.

Biomolecule/Target: GUK1

Alternates names: GMK, GMP kinase, Guanylate kinase

Synonyms: GMK, GMP kinase, Guanylate kinase

Background Information: GUK1, also known as GMK, belongs to the guanylate kinase family. This protein exists as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thereby playing an essential role in the recycling of GMP. Via its catalytic activity, GUK1 is thought to participate in regulating the supply of guanine nucleotides to signal transduction pathways. Overexpression of GUK1 is associated with pituitary adenocarcinomas, suggesting that GUK1 is involved in tumorigenesis. Recombinant human GUK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: GUK1

Gene ID: 2987

NCBI Accession: Q16774