Growth Hormone, chicken recombinant

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SKU:
4771-500
€185
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Description

Growth Hormone, chicken recombinant is available at Gentaur for Next week delivery.

A protein which plays an important role in growth control

Biomolecule/Target:

Alternates names: Growth hormone 1, Somatotropin, Pituitary growth hormone

Synonyms: Growth hormone 1, Somatotropin

Background Information: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Growth Hormone Chicken Recombinant (cGH) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids with an additional Ala at its N-terminus and having a molecular mass of 22255 Dalton. GH Chicken recombinant is purified by proprietary chromatographic techniques.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile H₂O or 0.4 % NaHCO₃ adjusted to pH 8-9 to a concentration ≥ 100 µg/ml and sterile filtered. This solution can then be diluted into other aqueous buffers, preferably in the presence of carrier protein.

NCBI Gene Symbol: SOMA

Gene ID: 378781

NCBI Accession: P08998

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Additional Information

Size:
500 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Chicken
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥99%
Assay:
SDS-PAGE
Purity:
≥99%
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
GH Chicken Recombinantis fully biologically active in homologous assays and in PDF-P1 3B9 cells stably transfected with rabbit GH receptors.
Results:
N/A
Molecular Weight:
22.255 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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