Growth Hormone, Bovine Recombinant

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SKU:
P1593-20
€185
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Description

Growth Hormone, Bovine Recombinant is available at Gentaur for Next week delivery.

A protein which plays an important role in growth control

Biomolecule/Target:

Alternates names: BGH, BST, rBGH, rBST, Bovine Somatotropin, Bovine GH, Growth hormone, GH1.

Synonyms: BGH, BST, rBGH, rBST, Bovine Somatotropin, Bovine GH, Growth hormone, GH1.

Background Information: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

Reconstitution Instructions: It is recommended to reconstitute the lyophilized Bovine Growth Hormone in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

NCBI Gene Symbol: GH1

Gene ID: 280804

NCBI Accession: P01246

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Additional Information

Size:
20 µg
Adwords:
FAUX
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Bovine
Recombinant:
VRAI
Source:
E. coli
Purity by SDS-PAGE:
0,98
Assay:
SDS - PAGE
Activity (Specifications/test method):
The activity as determined by the PDFP13B9 cells stably transfected with rabbit GH receptors. Bovine GH is also capable of forming a 1:2 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD).
Molecular Weight:
21.8 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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