Glycine N-methyltransferase, Human Recombinant

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SKU:
P1235-50
$183
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Description

Glycine N-methyltransferase, Human Recombinant is available at Gentaur for Next week delivery.

Regulate tissue concentration of AdoMet and metabolism of methionine.

Biomolecule/Target: GNMT

Alternates names: GNMT

Synonyms: GNMT

Background Information: Glycine N-methyltransferase, also known as GNMT, catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. This protein affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine and participates in the detoxification pathway in liver cells. Also it is reported that GNMT expression is diminished in human hepatocellular carcinoma (HCC). Recombinant human GNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: GNMT

Gene ID: 27232

NCBI Accession: Q14749

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E.coli
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per/μg
Activity (Specifications/test method):
Measured by its ability to transfer 1.0 nmole of methyl group per minute at 37C.
Biological activity:
Specific activity > 100 nmol/min/mg
Results:
>100 nmol/min/mg
Molecular Weight:
34.9 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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GNMT (Glycine N-methyltransferase) is available at Gentaur for Next Week Delivery. Product Short Name:  GNMT Other Names: [glycine N-methyltransferase; Glycine N-methyltransferase; glycine...
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