GAD1, human recombinant

GAD1, human recombinant is available at Gentaur for Next week delivery.

Catalyzes the production of GABA

Biomolecule/Target: GAD1

Alternates names: CPSQ1, GAD, SCP, Glutamate decarboxylase 1

Synonyms: CPSQ1, GAD, SCP, Glutamate decarboxylase 1

Background Information: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This protein may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Recombinant human GAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Reconstitution Instructions: N/A

NCBI Gene Symbol: GAD1

Gene ID: 2571

NCBI Accession: Q99259